Thursday, April 11, 2013

Microsoft leak details plans for two-step authentication process

Microsoft leak details plans for twostep authentication process

Smoke goes up. Lights fade. The crowd roars. It's 2003, and the Dave Matthews Band is about to perform what would go on to become the theme song for security processes the world over a decade later. Weird visualizations aside, it sure seems as if two-step authentication has become all the rage these days. With Google implementing the process in 2011, both Apple and Dropbox have followed, and Evernote has made clear that it's going to join the fray as soon as feasible. Now, leaked imagery is demonstrating that Microsoft might not be far behind, with a two-step verification process evidently planned for its online services.

As you'd expect, the process should work pretty simply once it's instituted -- you'll need to enable two-step on your account, and then use an app on your mobile device to retrieve randomized keys when logging into a computer that's not on your trusted device list. Notably, the process isn't expected to work with linked accounts, and while a Windows Phone app appears to already be floating about, there's no word on whether Android, BlackBerry or iOS users will receive the same courtesy. Till then, keep your passwords guarded. And, of course, watch the video embedded after the break.

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Source: LiveSide, Windows Phone Store

Source: http://www.engadget.com/2013/04/09/microsoft-leak-details-plans-for-two-step-authentication-process/

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Wednesday, April 10, 2013

What People in 1836 Thought the Moon Was Like

I wish I could live during a time when we believed creatures and aliens and things lived on the Moon. My imagination would have had so much fun! But alas, real life is too boring for that kind of fun. Still, in 1836, people believed that astronomers had found life on the moon. They imagined a world of hairy men with wings, unicorns and naked insect ladies. More »
    


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Early returns show wide lead for Kelly for Illinois seat (reuters)

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In gene therapy for breast cancer, the target is metastasis

Breast cancer remains the leading cancer diagnosis in women and, overall, the second-leading cause of cancer-related deaths in the U.S. The American Cancer Society reports that the five-year survival rate for women whose breast cancers are diagnosed at an early stage ? when the cancer cells are still localized ? is 98 percent. But if the breast cancer has metastasized, that five-year survival rate drops dramatically.

Now, City of Hope researcher Carlotta Glackin, Ph.D., associate professor in the Department of Neurosciences, has developed a drug that demonstrates in laboratory tests the ability to switch off metastasis in breast cancer cells. The findings were presented today at the annual meeting of the American Association for Cancer Research in Washington, D.C.

The process of breast cancer cells metastasizing to other areas in the body is influenced by the Twist1 gene.

The process of breast cancer cells metastasizing to other areas in the body is influenced by the Twist1 gene. Researchers are developing a gene therapy that turns off the gene.

Breast cancer stimulates metastasis by taking over a process known as epithelial-mesenchymal? transition. This process encourages cells to break apart from the tumor and travel through the body to new locations, usually another organ. To keep the epithelial-mesenchymal transition going, breast cancer cells turn on a gene known as Twist1 to produce high levels of Twist1 protein.

The research team focused on controlling Twist1 expression as a means to control metastasis of breast cancer cells. The Twist1 gene is considered a good target because it isn?t active in most normal, healthy situations. The research team wrote in the study abstract: ?Twist1 is also a desirable target because it is almost nonexistent in adult tissues and thus its silencing would have minimal side effects.?

Mobile Video Views Up 300% In 2012, With Tablets Driving The Charge With A 360% Increase

yt-devices-headerAdobe has released its Digital Video Benchmark for the U.S. for 2012, wherein the Digital Index team shows what it learned monitoring video performance throughout the year across digital platforms. The study compiles data from Adobe Marketing Cloud customers, scoring viewing habits and also monitoring ad performance. 2012 saw a massive increase in mobile viewership, according to Adobe's numbers, though desktop still dominates when it comes to online video.

Source: http://feedproxy.google.com/~r/Techcrunch/~3/nVikB6oI_KE/

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Annette Funicello: Disney family, costars, and famous fans mourn ...

ANNETTE-FUNICELLO-02.jpg

Image Credit: RB/Redferns

As news spreads of Annette Funicello?s passing at age 70 from Multiple Sclerosis-related complications, colleagues and fans have begun to share their fond remembrances of the former Mouseketeer and ?Beach Party? goer.

Lori Loughlin, costar in 1987?s Back to the Beach: ?Annette Funicello was really a wonderful person. I enjoyed working with her immensely and found her to be kind and down-to-earth. She faced her illness with courage and never wanted anyone to have pity on her. I have a fond memory of having lunch at her home many years ago and when she opened the cabinet to get something, there were rows of Skippy peanut butter. She was truly the embodiment of the friendly, all-American girl that we all loved to watch in the beach movies.?

Paul Anka, friend: ?Annette was a star from the time she was 12 years old, and I met her shortly after. In addition to her talent, she was self-possessed, determined, had incredible integrity, and was loved by everyone. When life threw her a terrible curve, she showed the best side of herself by coming forward to discuss her MS with courage and candor. As much as she entertained us as a young woman, she gave so much more by sharing her experience and raising awareness of this disease.

She was kind and intelligent and she will be missed by her family and her wide circle of friends, in which I was lucky to be included.?

Bob Iger, Chairman and CEO of The Walt Disney Company: ?Annette was and always will be a cherished member of the Disney family, synonymous with the word Mousketeer, and a true Disney Legend. She will forever hold a place in our hearts as one of Walt Disney?s brightest stars, delighting an entire generation of baby boomers with her jubilant personality and endless talent. Annette was well known for being as beautiful inside as she was on the outside, and she faced her physical challenges with dignity, bravery and grace. All of us at Disney join with family, friends, and fans around the world in celebrating her extraordinary life.?

Richard Sherman, Oscar-winning composer: ?Annette?s sweet, unassuming spirit, her love of people, and her capacity to exude kindness and good feelings to everyone she met was part of her beautiful charisma. Because the songs we wrote for her brought us to the attention of Walt, Bob and I always referred to Annette as our ?lucky star.? My wife, Elizabeth, joins me in sending a heartfelt aloha with much love to our ?Pineapple Princess.??

Diane Disney Miller, daughter of Walt Disney: ?Everyone who knew Annette loved and respected her. She was one of the loveliest people I?ve ever known, and was always so kind to everyone. She was also the consummate professional, and had such great loyalty to my father. Annette will always be very special to me and Ron [Miller, Diane's husband].?

Ron Miller, who helmed the Disney company in the 1980s and worked with Annette as a young assistant on?The Mickey Mouse Club: ?She was always in good spirits and ready to help out if she needed to step in when something unexpected happened.?

Fellow Mouseketeer and long-time friend Sharon Baird: ?Throughout all the years we were friends she never changed from that sweet person who cared so much about others. She always had time for everyone; family, friends and fans alike. It?s no wonder she was America?s sweetheart.?

Read more:
Former Mouseketeer Annette Funicello dies at 70
10 Most Successful Mouseketeers

Source: http://popwatch.ew.com/2013/04/08/annette-funicello-remembered/

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Tuesday, April 9, 2013

Fans get early look at 'Elysium' footage

(AP) ? The year is 2154, and Earth belongs to the poor. The wealthiest citizens live on "Elysium," an idyllic, disease-free utopia they built in space.

On Monday, a few hundred film fans in Los Angeles, Berlin and Sao Paolo got an early look at the future home of the 1 percent as imagined by "District 9" writer-director Neill Blomkamp.

Blomkamp showed about 10 minutes of footage from the anticipated film during a special screening. Matt Damon, who stars alongside Jodie Foster, introduced the footage in Berlin and appeared at Hollywood's Arclight Theater via satellite.

In the film, Earth is a trash-filled landscape policed unforgivingly by robotic droids. Flying military tanks patrol the sky.

Damon plays a diseased Earthling trying to infiltrate Elysium to save himself, and perhaps all of humanity. A group of Earth-bound rebels outfit him for the journey with a tentacled "strength suit." They use a drill to affix a digital box to his head that allows him to transfer brain contents as effortlessly as computer files.

Foster plays an Elysium administrator determined to keep Damon out. The star of "District 9," Sharlto Copley, plays a bearded villain who works on Earth to protect the wealthy space enclave.

Speaking to reporters after the screening, Blomkamp hinted that there could be a sequel to his breakthrough debut.

"I think the world of 'District 9' has a lot of very interesting race and impression-based ideas that I would still like to explore in that world," he said.

"Elysium" opens Aug. 9.

Associated Press

Source: http://hosted2.ap.org/APDEFAULT/4e67281c3f754d0696fbfdee0f3f1469/Article_2013-04-08-Film-Elysium-First%20Look/id-fe749a2adea3451097946b80a84f1e98

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Merkel tells Putin to give NGOs a chance

German Chancellor Angela Merkel, right, and Russian President Vladimir Putin, left, attend the opening of the Hannover Fair at the Congress Center in Hannover, Germany, Sunday April 7, 2013. (AP Photo/RIA Novosti, Alexei Druzhinin, Presidential Press Service)

German Chancellor Angela Merkel, right, and Russian President Vladimir Putin, left, attend the opening of the Hannover Fair at the Congress Center in Hannover, Germany, Sunday April 7, 2013. (AP Photo/RIA Novosti, Alexei Druzhinin, Presidential Press Service)

German Chancellor Angela Merkel welcomes Russian President Vladimir Putin for the opening of the Hannover Fair at the Congress Center in Hannover, Germany, Sunday April 7, 2013. (AP Photo/Frank Augstein)

German Chancellor Angela Merkel, center right, and Russian President Vladimir Putin, center left, pose for a photo at the opening of the Hannover Fair at the Congress Center in Hannover, Germany, Sunday April 7, 2013. (AP Photo/RIA Novosti, Alexei Druzhinin, Presidential Press Service)

(AP) ? Germany's leader has told Russian President Vladimir Putin that the Kremlin needs to encourage civil society as well as push for technological modernization, underlining tensions as Putin seeks to bolster economic ties with a visit to a major trade fair.

Putin's trip to the central German city of Hannover highlights Russia's interest in developing foreign trade, including further business ties with Germany. The two leaders were touring the fair on Monday.

At the opening of the event on Sunday, German Chancellor Angela Merkel said real modernization is enhanced by a strong civil society. Germany's ties with Russia have been strained lately by the Kremlin's heavy-handed response to opposition groups and pressure on non-governmental organizations.

Merkel said Germany was ready to help Russia diversify its economy, pointing to innovation, research and training as key points.

"We are convinced that this can best succeed if there is an active civil society," she said. "We must intensify this discussion ... and also give nongovernmental organizations ? the many groups that we in Germany know as motors of innovation ? a good chance in Russia."

A law approved last year in Russia requires all NGOs that receive funds from abroad and engage in vaguely defined political activities to register as "foreign agents," a term invoking Cold War-era spying connotations.

Leading Russian NGOs have pledged to boycott the bill. Putin responded by ordering wide-ranging checks of up to 2,000 NGOs across the country to check their compliance with the law. Among others targeted were two German think-tanks ? the Konrad Adenauer Foundation, which is aligned with Merkel's conservative Christian Democratic Union, and the Friedrich Ebert Foundation, linked to the opposition Social Democrats.

"I would have liked clearer words from the chancellor," Claudia Roth, a leader of Germany's opposition Greens, told ARD television. Roth said Russian NGOs face "repression ... defamation, discrediting and criminalization, and that simply requires very, very clear words."

Associated Press

Source: http://hosted2.ap.org/APDEFAULT/cae69a7523db45408eeb2b3a98c0c9c5/Article_2013-04-08-Germany-Russia/id-92682f2090f240ff99b51e8067342f4a

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Monday, April 8, 2013

Phantom Flex4K camera unveiled, blasts through 1000 4K frames per second (video)

Phantom Flex4K camera blasts through 1000 4K frames per second video

Vision Research just upped the 4k speed barrier by a near order of magnitude with the launch of its Phantom Flex4K cinema camera at NAB. Starting at $110K, it builds on its Phantom Flex predecessor with up to 1,000 fps in 5-second bursts at 4K, 2,000 fps in 2K and 3,000 fps at 720p resolution -- speeds that'll net you almost three minutes of 4K video when played back at 24 fps. The full 16:9 Super 35 sensor-equipped model can be had with PL, PV Canon EOS or Nikon F/G mounts and will capture RAW or compressed footage in an "industry-standard," but as-yet-unspecified format. The Flex4K will also be available with a Phantom Cinemag IV, which will hold up to 2TB of data, or nearly 2 hours of RAW 4K footage at normal recording speeds. Other features include a Bluetooth transmitter and handheld Phantom RCU for remote operation, 12+ stops of dynamic range, HD-SDI video output and a camera control interface and form factor that hews to industry norms, according to Vision Research. If you're still reading after seeing the six-figure price tag, check the videos or More Coverage link after the jump for more.

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Source: AbelCine

Source: http://www.engadget.com/2013/04/08/phantom-flex4k-camera-unveiled-at-NAB/

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Afghan attacks kill three US soldiers, four others, officials say

A car bomb attack killed six people, including three U.S. soldiers and an Afghan doctor, in southern Afghanistan on Saturday and an American civilian died in a separate attack in the east. NBC's Ron Mott reports.

By Ismail Sameem, Reuters

KANDAHAR, Afghanistan -- A car bomb attack killed six people, including three U.S. soldiers and an Afghan doctor, in southern Afghanistan on Saturday and an American civilian died in a separate attack in the east, local and international officials said.

The attacks came as the top U.S. general, Martin Dempsey, chairman of the Joint Chiefs of Staff, arrived in the country for a short visit to assess how much training Afghan troops need before U.S. troops pull out as planned by the end of 2014.

The American troops were traveling in a convoy of vehicles in Qalat, the capital of Zabul province, when the car bomb exploded. Provincial governor Mohammad Ashraf Nasery was unharmed but a local doctor and two foreign civilians also died, according to local and NATO officials.


The convoy was near a hospital and a NATO base at the time of the explosion. Five Afghans, including a student and two reporters, were wounded, a local official said.

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In a separate attack in Afghanistan's east, an American civilian working with the U.S. government was killed during an insurgent attack, the NATO-led International Security Assistance Force said in a statement.

Zabul shares borders with Pakistan to the southeast and the birthplace of the Taliban, Kandahar province, to the south.

The Taliban claimed responsibility for the Zabul attack in a text message from spokesman Qari Yousuf Ahmadi. He said a car bomb killed seven foreigners and wounded five others, though he later revised the toll to 13 foreigners killed and nine wounded.

The Taliban routinely exaggerates casualty figures.

The killings come in the wake of a bloody Taliban assault in the country's west on Wednesday that killed 44 people in a courtroom in Farah province. The United Nations says civilians are being increasingly targeted in 2013.

In a statement posted online earlier on Saturday, Taliban spokesman Ahmadi said the Taliban would continue to target Afghan judges and prosecutors.

"The Islamic Emirate, from today onwards, will keep a close watch over courthouses, all its personnel and all those who try to harm Mujahideen and will deal with them the same as the judges and prosecutors of Farah."

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Sunday, April 7, 2013

South Africa: Mandela discharged from the hospital

FILE - In this June 17, 2010 file photo, former South African President Nelson Mandela leaves the chapel after attending the funeral of his great-granddaughter Zenani Mandela in Johannesburg, South Africa. The South African presidency says Mandela has been discharged, Saturday, April 6, 2013, from a hospital after an improvement in his condition. Officials say he was treated for pneumonia. (AP Photo/Siphiwe Sibeko, Pool, File)

FILE - In this June 17, 2010 file photo, former South African President Nelson Mandela leaves the chapel after attending the funeral of his great-granddaughter Zenani Mandela in Johannesburg, South Africa. The South African presidency says Mandela has been discharged, Saturday, April 6, 2013, from a hospital after an improvement in his condition. Officials say he was treated for pneumonia. (AP Photo/Siphiwe Sibeko, Pool, File)

An ambulance believed to be transporting former president Nelson Mandela arrives at the home of Mandela in Johannesburg, Saturday, April 6, 2013. The South African Presidency has confirmed that Mandela has been discharged after spending nine days in hospital in Pretoria. Spokesman Mac Maharaj says the elder statesman was discharged, ?following a sustained and gradual improvement in his general condition,? and thanked all South Africans and people around the world for their support. He says Mandela will now receive home based high care. Mandela was admitted to hospital on March 27 with pneumonia. Since then the 94-year-old former statesman has had fluid drained from his lungs to ease his breathing. (AP Photo)

An ambulance believed to be transporting former president Nelson Mandela arrives at the home of Mandela in Johannesburg, Saturday, April 6, 2013. The South African Presidency has confirmed that Mandela has been discharged after spending nine days in hospital in Pretoria. Spokesman Mac Maharaj says the elder statesman was discharged, ?following a sustained and gradual improvement in his general condition,? and thanked all South Africans and people around the world for their support. He says Mandela will now receive home based high care. Mandela was admitted to hospital on March 27 with pneumonia. Since then the 94-year-old former statesman has had fluid drained from his lungs to ease his breathing. (AP Photo)

Visitors to Nelson Mandela Square in Johannesburg beneath a giant statue of the former president Monday, April 1, 2013. The presidential spokesman says former president Mandela spent Monday with family members in the hospital where he is being treated for a fifth day for a recurring lung infection that developed into pneumonia. The 94-year-old who helped free South Africa from white minority rule has had weak lungs ever since he quarried stone on Robben Island during some of his 27 years of imprisonment. He contracted tuberculosis there. (AP Photo/Denis Farrell)

Children play ball in front of a giant portrait of former president Nelson Mandela in a park in Soweto, South Africa, Sunday, March 31, 2013. Mandela remains in a hospital while he receives treatment for a recurrence of pneumonia. Presidential spokesman Mac Maharaj says there are no updates on 94 year old Mandela since an official statement Saturday on his condition. That statement reported the anti-apartheid leader was breathing without difficulty after having a procedure to clear fluid in his lung area. (AP Photo/Denis Farrell)

(AP) ? Former President Nelson Mandela was discharged from a hospital on Saturday following treatment for pneumonia, the presidency said in news that cheered South Africans who had waited tensely for health updates on a beloved national figure.

Mandela, the anti-apartheid leader who spent 27 years in prison for opposing white racist rule, was robust during his decades as a public figure, endowed with charisma, a powerful memory and an extraordinary talent for articulating the aspirations of his people and winning over many of those who opposed him. In recent years, however, 94-year-old Mandela became more frail and last made a public appearance at the 2010 World Cup soccer tournament, where he didn't deliver an address and was bundled against the cold in a stadium full of fans.

South Africans hold the former leader dear as a symbol of sacrifice and reconciliation stemming from his pivotal role in steering South Africa from the apartheid era and into democratic elections in 1994, at a time of great hope but also tension and uncertainty. The new South Africa, beset by economic inequality, crime and corruption, has not lived up to the soaring expectations of its people, but they still see hope through their icon, Mandela.

Primrose Mashoma, a South African, said she wished that Mandela would live, basically, forever.

"I wish him to stay maybe a hundred more years," she said.

A statement from the office of President Jacob Zuma said there had been "a sustained and gradual improvement" in the condition of Mandela, who was admitted to a hospital on the night of March 27.

"The former President will now receive home-based high care," the statement said.

Mandela had received similar treatment at his home in Johannesburg after a stay at a hospital in nearby Pretoria in December, when he was treated for a lung infection and had a procedure to remove gallstones. Earlier in March, the anti-apartheid leader was hospitalized overnight for what authorities said was a successful scheduled medical test.

During Mandela's latest hospitalization, doctors drained fluid from his lung area, making it easier for him to breathe.

On Saturday afternoon, shortly after the presidential statement on Mandela's discharge, a military ambulance was seen entering his home in the Johannesburg neighborhood of Houghton. In recent years, Mandela had been spending more time in Qunu, the rural area in Eastern Cape province where he grew up. But his delicate condition required that he be moved to South Africa's biggest city.

Many South Africans refer affectionately to Mandela by his clan name, Madiba. Buildings, squares, and other places have been named after him, and his image adorns statues and artwork around the country. The central bank issued new banknotes last year that show his smiling face.

"I'm really happy about Madiba coming out," said student Anele Gcolotela, using Mandela's clan name, a term of affection. "I think it's been too long now."

After Mandela's release from prison in 1990, he was widely credited with averting even greater bloodshed by helping the country in the transition to democratic rule, negotiating with the guardians of the same system that had deprived him of freedom for decades. He became South Africa's first black president in 1994 after elections were held, bringing an end to apartheid.

The Nobel Peace Prize laureate has been particularly vulnerable to respiratory problems since contracting tuberculosis during his 27-year imprisonment under apartheid. Most of those years were spent on Robben Island, a forbidding outpost off the coast of Cape Town where Mandela and other prisoners spent part of the time toiling in a stone quarry.

The elderly are especially vulnerable to pneumonia, which can be fatal. Its symptoms include fever, chills, a cough, chest pain and shortness of breath. Many germs cause pneumonia.

South African officials have said doctors were acting with extreme caution because of Mandela's advanced age.

In Saturday's statement, Zuma thanked the medical team and hospital staff that looked after Mandela and expressed gratitude for South Africans and people around the world who had shown support for Mandela. The South African government has sought to balance efforts to satisfy wide public interest in Mandela's condition with an intense campaign to preserve the privacy of an ailing figure who already has his place in history.

The African National Congress, the ruling party that led the struggle against apartheid and has held power since its demise, expressed its "happiness" at the discharge of its former leader from the hospital.

"We acknowledge the important role played by President Zuma and his office to keep the nation, the continent and the world informed about progress made on his treatment on a regular basis," the party said in a statement.

Associated Press

Source: http://hosted2.ap.org/APDEFAULT/3d281c11a96b4ad082fe88aa0db04305/Article_2013-04-06-South%20Africa-Mandela/id-334cb3650af9481db256e44182a63ee9

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Suspected cabin burglar on how he evaded capture

SALT LAKE CITY (AP) ? Troy James Knapp was dodging authorities, again.

The fugitive with a fondness for whiskey and a dislike of living near people had been wanted for a string of break-ins for years at cabins in Utah's mountains. With each near miss, each wanted poster and each threatening note left behind for law enforcement, the legend of him only grew.

Knapp survived by holing up inside the cabins, sleeping in the owners' beds, eating their food and listening to their AM radio for updates on the manhunt. And then, authorities say, he would take off, stealing items such as guns and high-end camping equipment and vanishing into the woods where he lived off dandelions and wild game.

Over Easter weekend, authorities were on his trail, again.

By Tuesday, his life on the lam came to an end, done in by an educated guess by searchers who had grown to know his tendencies, the tracks he left with his snowshoes and the sounds of him chopping wood outside a cabin near a mountain reservoir.

A team of 14 officers approached him on snowshoes ? the only way to quietly sneak up on him ? and called in reinforcements to help corner the bearded and camouflage-clad fugitive, a trim 45-year-old standing 5-foot-8.

Now in police custody, Knapp is telling authorities how he managed to evade them for so long across a mountainous region stretching for 180 miles. "He really has a fascinating story to tell, and right now he's willing to tell it," Sanpete County Sheriff Brian Nielson said.

Knapp, born in Saginaw, Mich., got into trouble with the law early. As a teenager, he was convicted of breaking and entering, passing bad checks and unlawful flight from authorities, according to court records. His most serious offense, an arrest for felony assault in Michigan, was reduced in 1994 to a charge of malicious destruction of property after he agreed to plead guilty.

"He says, 'I don't hate people. I just don't like living with them,'" Sevier County Sheriff Nathan Sheriff Curtis said.

With no known occupation, Knapp drifted across the country and ended up in prison in California for burglary. He fell off the radar in 2004 when he "went on the run" while on parole, said Bobby Haase, a spokesman for the California Department of Corrections and Rehabilitation.

By 2007, Utah authorities began investigating a string of cabin burglaries they believed were tied to one person. It wasn't until early 2012 that they identified Knapp as the suspect from cabin surveillance photos and fingerprints lifted from one cabin. In one photo, he was wearing camouflage, a rifle was slung over his shoulder and he had purple-colored aluminum snowshoes on his feet. Knapp appears to have aged considerably from a 2001 California mug shot.

Tracy Glover, chief deputy sheriff in Kane County, said it was fairly easy to identify Knapp's cabin habits. Knapp would drink any coffee and alcohol he could find, authorities say. Unlike typical burglars, he never took large or expensive appliances such as TVs or stereos. He took only what he could carry, mostly camping gear and weapons he stashed in abundance in the woods. He returned to burglarize cabins more than once, even swapping one stolen rifle for another, officials said.

A few years ago, investigators found an abandoned camp they linked to Knapp. It had a doomsday supply of dehydrated foods, radios, batteries, high-end camping gear, 19 guns and a copy of Jon Krakauer's "Into the Wild," a book about a young man who died after wandering into the Alaskan wilderness to live alone off the land.

It was in Kane County, near Zion National Park, where authorities lifted Knapp's fingerprints from items in a cabin. The prints matched sets in criminal databases, giving law enforcement confidence that he was their guy.

Knapp is believed to have left that area in early 2012. He started to make his way north from Kane into Sevier, Sanpete and Emery counties, where he was occasionally spotted by hunters. Knapp has told detectives he was feeling stressed trying to hide from hunters last fall, said Brian Nielson, the sheriff in Sanpete County.

Court records from multiple Utah counties indicate Knapp regularly spent several days in snowbound cabins, exhausting the food and firewood before moving on. Authorities say the signature clue of his presence was an empty bottle of whiskey. In summer, he retreated to makeshift camps deep in the backcountry.

He sometimes tidied up a cabin, but other times left it a mess or riddled with bullets, authorities say. He was known to deface religious icons. He scrawled notes for cabin owners, alternatively thanking them or demanding they "get off my mountain." He also warned sheriffs he was "gonna put you in the ground!"

Even authorities have found something to admire in Knapp's knack for survival and evasion. He stepped on saplings to avoid leaving discernible boot tracks and changed stolen footwear often to confuse searchers. He walked alongside trails instead of on them and kept mostly to backcountry.

He used some of those tactics in his final flight, which started more than a dozen miles away from his capture site. At Joe's Valley in the Manti-LaSal National Forest, deputies found boot prints around two burglarized cabins. The tracks led in no apparent direction, Emery County sheriff's Cpt. Jeff Thomas said.

Deputies copied his silent mode of travel on snowshoes over three days and nights as they tried to track Knapp across rugged terrain, first losing his size-10 shoe prints, then regaining his tracks on snowshoe as he ventured higher on the 10,000-foot Wasatch Plateau.

"They stayed quiet and built no fires ? and they were very cold," Thomas said.

To get this far, deputies had to think like Knapp. He moved often and swiftly across the backcountry, covering 20 miles in a day "and that was nothing for him," Curtis said.

They had to imagine where Knapp might have taken off. They guessed it was a collection of cabins a dozen miles away at a high-altitude reservoir. They believe Knapp had visited there before. Along the way, they picked up his snowshoe tracks.

With 13 cabins at the reservoir, "we didn't know exactly where he was," U.S. Forest Service officer Scott Watson said. "We couldn't just go knocking on doors."

By 10 a.m. Tuesday, 40 officers took positions around the 9,000-foot reservoir. Knapp fired off a handful of shots at a helicopter that flushed him out of a cabin. He tried to escape into the woods, but ran into three armed officers. He laid down his rifle and surrendered.

The last three nights Knapp spent as a fugitive were in a framed log cabin with a commanding view of forest roads leading to Ferron Reservoir. Owner Eugene Bartholomew said "it was kind of messed up" and "stunk like crazy." It wasn't his only discovery. On television news, Bartholomew took his first look at Knapp.

"That son-of-a-bitch has got my coat on," he said.

Source: http://news.yahoo.com/utah-cabin-burglar-ends-long-run-wilderness-151312517.html

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Researchers log rise in anti-Semitic incidents

TEL AVIV, Israel (AP) ? An annual Israeli report has logged a 30 percent rise in anti-Semitic incidents worldwide, linking the surge to Europe's economic troubles and a deadly attack on Jewish schoolchildren last year in France.

Tel Aviv University said Sunday that 686 attacks were recorded in 34 countries, ranging from physical violence to vandalism of synagogues and cemeteries, compared to 526 in 2011. The sharp increase followed a two-year decline.

It linked the March 2012 shooting at a Jewish school in Toulouse, where an extremist Muslim gunman killed four, to a series of copycat attacks, particularly in France, where physical assaults on Jews almost doubled.

In Greece, Hungary and Ukraine, economic difficulties favored the rise of extreme right-wing parties whose anti-Semitic and anti-Israeli rhetoric has apparently helped ignite attacks, it said.

Source: http://news.yahoo.com/researchers-log-rise-anti-semitic-incidents-082254461.html

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Mitochondrial metabolic regulator SIRT4 guards against DNA damage

Friday, April 5, 2013

Healthy cells don't just happen. As they grow and divide, they need checks and balances to ensure they function properly while adapting to changing conditions around them.

Researchers studying a set of proteins that regulate physiology, caloric restriction and aging have discovered another important role that one of them plays. SIRT4, one of seven sirtuin proteins, is known for controlling fuel usage from its post in the mitochondria, the cell's energy source. It responds to stressful changes in the availability of nutrients for the cell.

New research reveals that SIRT4 is also extremely sensitive to a different form of stress: DNA damage. This unsuspected response by the metabolic checkpoint means SIRT4 doubles as a sentry guarding against cancer, which is spurred by genetic abnormalities.

Sirtuins have become familiar for their connection to longevity and to resveratrol, the red-wine compound that activates SIRT1, but less attention has been focused on SIRT3, SIRT 4 and SIRT5, all of which are found in mitochondria. Marcia Haigis, HMS associate professor of cell biology, led a team that has uncovered SIRT4 as an important player in the DNA damage response pathway, coordinating a sequence of events that normally result[s] in tumor suppression. They published their results April 4 in Cancer Cell.

"When we started studying SIRT4, we were focused only on its metabolic role, looking for functions related to diabetes and obesity," said Haigis. "What we found, to our surprise, was that SIRT4 was responsive to DNA damage, so that led us to investigate the metabolic response to DNA damage and how SIRT4 controls the metabolic response to genotoxic stress."

To see how SIRT4 normally functions, Haigis and her colleagues induced DNA damage by exposing cells in a lab dish to ultraviolet light. This damage triggered a halt in glutamine metabolism, limiting the amount of nutrients the cell could use as it goes through a cycle of division and growth.

Blocking the cell cycle at this juncture is important. If cell growth after DNA damage goes unchecked, proliferation of impaired cells can lead to cancer. When SIRT4 works properly, this chain of events is broken before bad cells and their abnormal genes multiply. SIRT4 blocks glutamine metabolism, arrests the cell cycle and suppresses tumor formation.

The scientists tested this SIRT4 response in mice. Bred to lack the gene that encodes the SIRT4 protein but otherwise normal, the mice spontaneously developed lung cancer by 15 months.

"When SIRT4 is missing, you don't have this metabolic checkpoint involving glutamine, which is important because glutamine is an amino acid required for proliferation in the cell," Haigis said. "Without SIRT4, the cell keeps dividing even in the face of DNA damage, so the cell accumulates more damage."

The scientists also analyzed data showing SIRT4 gene expression levels are low in several human cancers, including small-cell lung carcinoma, gastric cancer, bladder carcinoma, breast cancer and leukemia.

While they cannot say if SIRT4 loss alone will initiate cancer, its absence appears to create an environment in which tumor cells survive and grow.

"Our findings suggest that SIRT4 may be a potential target against tumors," they conclude.

###

Harvard Medical School: http://hms.harvard.edu

Thanks to Harvard Medical School for this article.

This press release was posted to serve as a topic for discussion. Please comment below. We try our best to only post press releases that are associated with peer reviewed scientific literature. Critical discussions of the research are appreciated. If you need help finding a link to the original article, please contact us on twitter or via e-mail.

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Source: http://www.labspaces.net/127612/Mitochondrial_metabolic_regulator_SIRT__guards_against_DNA_damage

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Obama Calls Californian Kamala Harris 'Best Looking' Attorney General

President Obama assessed the beauty of California's attorney general Kamala Harris, calling her "the best looking attorney general," during remarks at a fundraiser in Atherton, California.

"You have to be careful to, first of all, say she is brilliant and she is dedicated and she is tough, and she is exactly what you'd want in anybody who is administering the law, and making sure that everybody is getting a fair shake. She also happens to be by far the best-looking attorney general in the country - Kamala Harris is here."

"It's true! C'mon," he said as the crowd laughed, according to a report provided by a print reporter at the home of John Goldman, an heir to the Levi-Strauss fortune.

"And she is a great friend and has just been a great supporter for many, many years. She's brilliant and she's dedicated," Obama said at a luncheon fundraiser benefiting the DNC.

Harris has served as California's attorney general since 2011 and is a rising star for Democrats. She is often mentioned as a potential candidate for governor.

The president came under some fire back in 2008 when he referred to a female reporter as " sweetie " and told her to hold a question for a press availability.

Here is an interview Harris did with ABC News and Yahoo! during last summer's Democratic National Convention:

Obama's event in California wrapped a two day, four fundraiser sweep through the Bay Area. Earlier Thursday he talked about the need for new gun control at the home of Liz Simons and Mark Heising, director of a San Francisco investment firm and a board member at the Environmental Defense Fund

Read about his comments on gun control and immigration by clicking HERE .

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Source: http://news.yahoo.com/obama-calls-californian-kamala-harris-best-looking-attorney-211610335--abc-news-politics.html

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Friday, April 5, 2013

Dozens killed after building collapses near Mumbai

Dozens of people are dead after a building collapsed in Mumbai, India, with many more missing in the rubble. The building was under construction when it collapsed. Families had moved into the unfinished structure.

Rafiq Maqbool / AP

Rescue workers look for trapped people after a residential building collapsed in Thane, Mumbai, India, Thursday, April 4, 2013.

By Reuters

At least 39 people were killed and dozens injured after an illegal, half-constructed building collapsed in seconds "like a pack of cards" on the outskirts of India's financial centre Mumbai, officials and witnesses said.

Rescue workers using cranes and bulldozers searched for survivors in the wreck of steel and concrete on Friday after the seven-storey building crumbled on Thursday night. Residents said laborers paying rent of around $5 a day had lived in it.

"The building collapsed like a pack of cards within three to four seconds," said Ramlal, a local resident. "It just tilted a bit and collapsed," he said. Read the full story.

Danish Siddiqui / Reuters

Rescue workers carry a woman who survived from the collapsed building.

Vivek Prakash / Reuters

Rescue workers search for survivors at the site of the collapsed building.

Danish Siddiqui / Reuters

Rescue workers carry a child who survived the collapse of a residential building in Thane.

Divyakant Solanki / EPA

Rescue work continued at the site of the building collapse on April 5, 2013.

AP

Rescue workers carry a young child who survived the building collapse on Friday, April 5, 2013.

?

This story was originally published on

Copyright 2013 Thomson Reuters. Click for restrictions.

Source: http://feeds.nbcnews.com/c/35002/f/653387/s/2a5cc123/l/0Lphotoblog0Bnbcnews0N0C0Inews0C20A130C0A40C0A40C1760A4150A0Edozens0Ekilled0Eafter0Ebuilding0Ecollapses0Enear0Emumbai0Dlite/story01.htm

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Boeing to conduct Dreamliner flight to test battery?

Boeing said Friday it had conducted a test flight of the Dreamliner 787 to evaluate a new battery system, which is aimed at overcoming the problems that led to the fleet's grounding in January.

In a statement released Friday afternoon, Boeing said the nearly two-hour flight was uneventful and was completed at 12:28 p.m. Pacific time. The airplane took off and landed at Paine Field, near the company's manufacturing operation in Everett, Wash.

Eleven people were on board the plane, including two representatives of the Federal Aviation Administration.

The test flight was meant to gather information the airplane makerhopes will convince the Federal Aviation Administration that the new batteries will not overheat or catch fire. Boeing said the next step was to gather and analyze data, which it would then deliver to the FAA in coming days.

Earlier, Transportation Secretary Ray LaHood said he thought Boeing has a "good plan" to fix the battery problem, but added that he wants to ensure the Dreamliner is safe before allowing the planes back in the air, and no decision had been made on commercial flights.

"They're doing the tests now, and we've agreed with the tests that they're doing. And when they complete the tests, they'll give us the information and we'll make a decision," LaHood said at the U.S. Export-Import Bank's annual conference in Washington.

The certification flight is part of a series of tests to show whether measures Boeing has devised to fix the battery problems work as intended. A preparation flight on March 25 "went according to plan," Boeing said.

It's still unknown what caused the batteries to overheat, and the National Transportation Safety Board is investigating. But Boeing came up with measures it says make the battery safe. It put more insulation in the battery, encased the battery in a steel box, changed the circuitry of the battery charger and added a titanium venting tube to expel heat and fumes outside the plane.

Once Boeing completes its testing, the FAA and other global regulators will review the test data and decide whether to certify the fix and return the plane to service.

Airlines have been barred from using the plane since it was grounded in January, and Boeing has been barred from delivering 787s, though it continues to build the plane. The delay has been costing the company an estimated $50 million a week.

Reuters contributed to this report.

Source: http://feeds.nbcnews.com/c/35002/f/653351/s/2a61f969/l/0L0Snbcnews0N0Cbusiness0Cboeing0Econduct0Edreamliner0Eflight0Etest0Ebattery0E1B9229444/story01.htm

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A model predicts that the world's populations will stop growing in 2050

A model predicts that the world's populations will stop growing in 2050 [ Back to EurekAlert! ] Public release date: 4-Apr-2013
[ | E-mail | Share Share ]

Contact: SINC
info@agenciasinc.es
34-914-251-820
FECYT - Spanish Foundation for Science and Technology

Global population data spanning the years from 1900 to 2010 have enabled a research team from the Autonomous University of Madrid to predict that the number of people on Earth will stabilise around the middle of the century. The results, obtained with a model used by physicists, coincide with the UN's downward forecasts.

According to United Nations' estimates, the world population in 2100 will be within a range between 15.8 billion people according to the highest estimates high fertility variant and 6.2 billion according to the lowest low fertility variant, a figure that stands below the current 7 billion.

A mathematical model developed by a team from the Autonomous University of Madrid (UAM) and the CEU-San Pablo University, both from Spain, seems to confirm the lower estimate, in addition to a standstill and even a slight drop in the number of people on Earth by the mid-21st century.

The population prospects between 1950 and 2100 provided by the UN were used to conduct the study, published in the journal 'Simulation'. Mathematical equations which are used in scientific fields, such as condensed matter physics, were then applied to this data.

"This is a model that describes the evolution of a two-level system in which there is a probability of passing from one level to another," as explained to SINC by Flix F. Muoz, UAM researcher and co-author of the project.

The team considered the Earth as a closed and finite system where the migration of people within the system has no impact and where the fundamental principle of the conservation of mass biomass in this case and energy is fulfilled.

"Within this general principle, the variables that limit the upper and lower zone of the system's two levels are the birth and mortality rates," Muoz pointed out and recalled the change that occurred in the ratio between the two variables throughout the last century.

"We started with a general situation where both the birth rate and mortality rate were high, with slow growth favouring the former," he added, "but the mortality rate fell sharply in the second half of the 20th century as a result of advances in healthcare and increased life expectancy and it seemed that the population would grow a lot.

However, the past three decades have also seen a steep drop-off in the number of children being born worldwide."

The model's S-shaped sigmoid curve reflects this situation with an inflection point in the mid-1980s when the speed at which the population is growing starts to slow down until it stabilises around 2050.

The data also reflect the downward trend in the UN's series of prospects. "Overpopulation was a spectre in the 1960s and 70s but historically the UN's low fertility variant forecasts have been fulfilled," Muoz highlighted.

As recently as 1992 it was predicted that there would be 7.17 billion people on Earth by 2010 instead of the actual 6.8 billion. In fact, the fertility rate has fallen by more than 40% since 1950.

"This work is another aspect to be taken into consideration in the debate, although we do not deal with the significant economic, demographic and political consequences that the stabilisation and ageing of the world population could entail," the researcher concluded.

###

References:

Julio A Gonzalo, Flix-Fernando Muoz, David J Santos. "Using a rate equations approach to model World population trends". Simulation: Transactions of the Society for Modeling and Simulation International 89: 192-198, February 2013.


[ Back to EurekAlert! ] [ | E-mail | Share Share ]

?


AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.


A model predicts that the world's populations will stop growing in 2050 [ Back to EurekAlert! ] Public release date: 4-Apr-2013
[ | E-mail | Share Share ]

Contact: SINC
info@agenciasinc.es
34-914-251-820
FECYT - Spanish Foundation for Science and Technology

Global population data spanning the years from 1900 to 2010 have enabled a research team from the Autonomous University of Madrid to predict that the number of people on Earth will stabilise around the middle of the century. The results, obtained with a model used by physicists, coincide with the UN's downward forecasts.

According to United Nations' estimates, the world population in 2100 will be within a range between 15.8 billion people according to the highest estimates high fertility variant and 6.2 billion according to the lowest low fertility variant, a figure that stands below the current 7 billion.

A mathematical model developed by a team from the Autonomous University of Madrid (UAM) and the CEU-San Pablo University, both from Spain, seems to confirm the lower estimate, in addition to a standstill and even a slight drop in the number of people on Earth by the mid-21st century.

The population prospects between 1950 and 2100 provided by the UN were used to conduct the study, published in the journal 'Simulation'. Mathematical equations which are used in scientific fields, such as condensed matter physics, were then applied to this data.

"This is a model that describes the evolution of a two-level system in which there is a probability of passing from one level to another," as explained to SINC by Flix F. Muoz, UAM researcher and co-author of the project.

The team considered the Earth as a closed and finite system where the migration of people within the system has no impact and where the fundamental principle of the conservation of mass biomass in this case and energy is fulfilled.

"Within this general principle, the variables that limit the upper and lower zone of the system's two levels are the birth and mortality rates," Muoz pointed out and recalled the change that occurred in the ratio between the two variables throughout the last century.

"We started with a general situation where both the birth rate and mortality rate were high, with slow growth favouring the former," he added, "but the mortality rate fell sharply in the second half of the 20th century as a result of advances in healthcare and increased life expectancy and it seemed that the population would grow a lot.

However, the past three decades have also seen a steep drop-off in the number of children being born worldwide."

The model's S-shaped sigmoid curve reflects this situation with an inflection point in the mid-1980s when the speed at which the population is growing starts to slow down until it stabilises around 2050.

The data also reflect the downward trend in the UN's series of prospects. "Overpopulation was a spectre in the 1960s and 70s but historically the UN's low fertility variant forecasts have been fulfilled," Muoz highlighted.

As recently as 1992 it was predicted that there would be 7.17 billion people on Earth by 2010 instead of the actual 6.8 billion. In fact, the fertility rate has fallen by more than 40% since 1950.

"This work is another aspect to be taken into consideration in the debate, although we do not deal with the significant economic, demographic and political consequences that the stabilisation and ageing of the world population could entail," the researcher concluded.

###

References:

Julio A Gonzalo, Flix-Fernando Muoz, David J Santos. "Using a rate equations approach to model World population trends". Simulation: Transactions of the Society for Modeling and Simulation International 89: 192-198, February 2013.


[ Back to EurekAlert! ] [ | E-mail | Share Share ]

?


AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.


Source: http://www.eurekalert.org/pub_releases/2013-04/f-sf-amp040413.php

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Connecticut House passes sweeping gun measure (CNN)

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Thursday, April 4, 2013

Reynolds lifts Tribe over now 0-2 Jays in 11th

By IAN HARRISON

Associated Press

Associated Press Sports

updated 10:58 p.m. ET April 3, 2013

TORONTO (AP) - Mark Reynolds made his first hit of the new season a winner.

Reynolds hit a tiebreaking home run in the 11th inning and the Cleveland Indians beat the Toronto Blue Jays 3-2 on Wednesday night.

"I'm just happy I got my first hit," said Reynolds, who was 0 for 7 with three strikeouts before his big blast. "I didn't care if it was a go-ahead homer or not."

Reynolds drilled a leadoff shot into the second deck off Sergio Santos (0-1), the fifth Blue Jays reliever.

"He's going to miss sometimes, but when he does that, it's a game changer and it was tonight," Indians manager Terry Francona said of Reynolds, who set a major league record with 223 strikeouts in 2009.

The drive helped the Indians overcome a blown save by Chris Perez, who surrendered a tying shot by Jose Bautista in the ninth but was happy to see Reynolds bail him out.

"That was a big hit for us," Perez said of Reynolds' homer. "He crushed it."

The overhauled Blue Jays lost their second straight to begin the season. Toronto's offense has just three runs and nine hits in two games.

"This team's built to score runs," Blue Jays manager John Gibbons said. "We haven't done that yet. But we're going to hit."

Toronto dropped its first two games of the season for the first time since an 0-3 start in 2004, but Bautista denied that high expectations were causing the Blue Jays to press.

"No," he said. "That's a big N-O. Both capital letters."

Cleveland's Michael Brantley went 4 for 5 with an RBI, the fifth four-hit game of his career.

Matt Albers (1-0) got one out for the win, and Joe Smith finished for his first save.

The Indians took a 2-1 lead in the eighth against reliever Darren Oliver. Nick Swisher led off with a walk and moved to second on Brantley's fourth single. Carlos Santana hit a grounder to third, where Swisher was forced out, but Maicer Izturis' throw to first sailed wide, allowing Brantley to score.

Bautista tied it with a one-out shot to left off Perez in the ninth. Bautista had gone hitless in his first three at-bats, grounding into a pair of inning-ending double plays.

After Bautista swung and missed a first-pitch slider, Perez tried to sneak a fastball past the Blue Jays slugger.

"I had good movement on it," Perez said. "It just caught too much of the plate."

Edwin Encarnacion followed with a walk, but Perez sent it to extra innings by getting Adam Lind and J.P. Arencibia to fly out.

The Indians opened the scoring in the third. Michael Bourn led off with a double just beyond the reach of Izturis at third. Two outs later, Swisher walked and Brantley followed with an RBI single between third and short.

Izturis tied it in the bottom half with a leadoff drive to right, his first, and Toronto's first homer of the new season.

Cleveland starter Ubaldo Jimenez, who lost a career-high 17 games last season and ended the year with nine straight road losses, looked sharp in his season debut.

"I thought he was outstanding," Francona said. "His secondary stuff, his direction to the plate was down. His offspeed, especially his changeup, was really good."

Jimenez allowed one run and three hits in six innings, walked two and struck out six.

"I felt really good," Jimenez said. "That's a tough lineup. They have everything. They can run, they can hit for power."

Brantley and Santana hit consecutive singles in the sixth, but Blue Jays starter Brandon Morrow ended his outing by getting Reynolds to ground into a double play.

Morrow allowed one run and six hits in six innings. He walked two and struck out eight.

NOTES: Indians LHP Scott Kazmir will miss his first scheduled start of the season, Saturday at Tampa Bay, because of a sore abdominal muscle on his right side. Kazmir will return to Cleveland for tests and rejoin the team before Friday's game against the Rays. ... The Indians claimed right-hander Robert Whitenack on waivers from the Chicago Cubs and optioned him to Double-A Akron. Cleveland also transferred RHP Frank Herrmann (right elbow) to the 60-day DL. ... Blue Jays manager John Gibbons said backup Henry Blanco will "probably" catch the next start by knuckleballer R.A. Dickey. Arencibia had three passed balls in Dickey's debut Tuesday. ... Attendance was 24,619, about half the size of Tuesday's opening night crowd of 48,857. ... Cleveland 2B Jason Kipnis celebrated his 26th birthday.

? 2012 The Associated Press. All rights reserved. This material may not be published, broadcast, rewritten or redistributed.


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Posnanski: Everybody knows that we don?t have much patience in America. So with every team having played at least one game in the Majors, here's an updated look at the awards races.

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